Ofufuza ku University of Central Florida apanga mankhwala ophera tizilombo toyambitsa matenda omwe amatha kupha ma virus padziko lapansi mpaka masiku 7-kupeza komwe kumatha kukhala chida champhamvu polimbana ndi COVID-19 ndi ma virus ena omwe akubwera.
Kafukufukuyu adasindikizidwa sabata ino mu nyuzipepala ya ACS Nano ya American Chemical Society ndi gulu lamitundu yambiri la akatswiri a virus ndi engineering ochokera ku yunivesite komanso wamkulu wa kampani yaukadaulo ku Orlando.
M'masiku oyambilira a mliriwu, a Christina Drake, a UCF alumnus komanso woyambitsa Kismet Technologies, adadzozedwa atapita ku golosale kukapanga mankhwala ophera tizilombo. Kumeneko, anaona wantchito akupopera mankhwala ophera tizilombo pa chogwirira cha firiji ndipo nthawi yomweyo anapukutapo mankhwalawo.
Iye anati: “Poyamba maganizo anga anali oti ndipange mankhwala ophera tizilombo omwe sagwira ntchito msanga, koma tinakambirana ndi ogula, monga madokotala ndi madokotala a mano, kuti tidziwe mankhwala amene akufuna. Kwa iwo Chinthu chofunika kwambiri ndi chimene chili chokhalitsa. Ipitilizabe kupha tizilombo tolumikizana kwambiri monga zogwirira zitseko ndi pansi kwa nthawi yayitali ikatha kugwiritsa ntchito. ”
Dr. Ndi ndalama zochokera ku National Science Foundation, Kismet Tech, ndi Florida High-Tech Corridor, ofufuza adapanga mankhwala opha tizilombo toyambitsa matenda opangidwa ndi nanoparticle.
Zomwe zimagwiritsidwa ntchito ndi nanostructure yotchedwa cerium oxide, yomwe imadziwika ndi mphamvu zake zotsitsimutsa antioxidant. Cerium oxide nanoparticles amasinthidwa ndi siliva pang'ono kuti apange mphamvu yolimbana ndi tizilombo toyambitsa matenda.
Seal, yemwe wakhala akuphunzira sayansi ya nanotechnology kwa zaka zoposa 20, anati: “Zimagwira ntchito mu chemistry ndi makina. "Nanoparticles amatulutsa ma electron kuti awononge kachilomboka ndikupangitsa kuti zisagwire ntchito. Mwamwayi, amadziphatikizanso ndi kachilomboka ndikung'ambika pamwamba ngati baluni yophulika. ”
Nthawi zambiri zopukuta kapena zopopera zitha kupha tizilombo pamwamba patatha mphindi zitatu kapena zisanu ndi chimodzi mutagwiritsa ntchito, koma palibe chotsalira. Izi zikutanthauza kuti pamwamba pafunika kupukuta mobwerezabwereza kuti ikhale yaukhondo kupewa kutenga ma virus angapo monga COVID-19. Mapangidwe a nanoparticle amakhalabe okhoza kuyambitsa tizilombo toyambitsa matenda ndipo akupitiriza kupha tizilombo toyambitsa matenda padziko lapansi kwa masiku 7 mutatha kugwiritsa ntchito kamodzi.
"Matenda ophera tizilombo amawonetsa ntchito yayikulu yolimbana ndi ma virus asanu ndi awiri osiyanasiyana," Parks adalongosola, ndipo labotale yake ndiyomwe imayang'anira kukana kwa "dikishonale" ya kachilomboka. "Sizinangowonetsa ma antivayirasi olimbana ndi ma coronaviruses ndi ma rhinoviruses, komanso zidawoneka zogwira ntchito motsutsana ndi ma virus ena osiyanasiyana okhala ndi mawonekedwe osiyanasiyana komanso zovuta. Tikukhulupirira kuti ndi luso lodabwitsali lakupha, mankhwala ophera tizilombowa adzakhalanso chida chothandiza kwambiri polimbana ndi ma virus ena omwe angotuluka kumene. ”
Asayansi amakhulupirira kuti yankho limeneli lidzakhudza kwambiri chilengedwe cha chisamaliro chaumoyo, makamaka kuchepetsa chiwerengero cha matenda opatsirana kuchipatala-monga methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa ndi Clostridium difficile - Izi zidzayambitsa matenda omwe amakhudza kwambiri kuposa gawo limodzi mwa magawo atatu a odwala omwe adagonekedwa ku zipatala zaku US.
Mosiyana ndi mankhwala ambiri ophera tizilombo, njira imeneyi ilibe mankhwala owopsa, zomwe zimasonyeza kuti ndi zotetezeka kugwiritsa ntchito pamtunda uliwonse. Malinga ndi zomwe bungwe la US Environmental Protection Agency likufuna, kuyezetsa koyang'anira khungu ndi kuyabwa kwamaso sikuwonetsa zotsatira zoyipa.
"Njira zambiri zophera tizilombo m'nyumba zomwe zilipo pakadali pano zili ndi mankhwala omwe ndi owopsa m'thupi atawonekera mobwerezabwereza," adatero Drake. "Zogulitsa zathu zopangidwa ndi nanoparticle zidzakhala ndi chitetezo chokwanira, chomwe chidzathandiza kwambiri kuchepetsa kukhudzidwa kwa anthu ndi mankhwala."
Kafukufuku wochulukirapo akufunika zinthu zisanalowe mumsika, ndichifukwa chake gawo lotsatira la kafukufuku lidzayang'ana kwambiri momwe mankhwala ophera tizilombo amagwirira ntchito kunja kwa labotale. Ntchitoyi iphunzira momwe mankhwala ophera tizilombo amakhudzidwa ndi zinthu zakunja monga kutentha kapena kuwala kwa dzuwa. Gululi likukambirana ndi netiweki yachipatala yakumaloko kuti ayesere mankhwalawa m'malo awo.
Drake anawonjezera kuti: "Tikuyang'ananso kakulidwe ka filimu yosakhalitsa kuti tiwone ngati tingatseke ndikutseka zipatala kapena zogwirira zitseko, madera omwe akuyenera kupha tizilombo toyambitsa matenda, kapena madera omwe akulumikizana mosalekeza."
Seal adalumikizana ndi UCF's department of Materials Science and Engineering mu 1997, yomwe ndi gawo la UCF School of Engineering ndi Computer Science. Amagwira ntchito kusukulu ya udokotala ndipo ndi membala wa gulu la prosthetic la UCF Biionix. Iye ndi mkulu wakale wa UCF Nano Science and Technology Center ndi Advanced Materials Processing and Analysis Center. Analandira PhD mu engineering engineering kuchokera ku yunivesite ya Wisconsin, ali ndi mwana wamng'ono mu biochemistry, ndipo ndi wofufuza pambuyo pa udokotala ku Lawrence Berkeley National Laboratory ku yunivesite ya California, Berkeley.
Atagwira ntchito ku Wake Forest School of Medicine kwa zaka 20, Parkes adabwera ku UCF ku 2014, komwe adakhala pulofesa komanso wamkulu wa dipatimenti ya Microbiology ndi Immunology. Iye analandira Ph.D. mu biochemistry kuchokera ku yunivesite ya Wisconsin ndipo ndi wofufuza wa American Cancer Society ku Northwestern University.
Kafukufukuyu adalembedwa ndi Candace Fox, wofufuza pambuyo pa UCF School of Medicine, Craig Neal wochokera ku UCF School of Engineering ndi Computer Science, ndi ophunzira omaliza maphunziro a Tamil Sakthivel, Udit Kumar, ndi Yifei Fu ochokera ku UCF School of Engineering ndi Computer Science. .
Zida zoperekedwa ndi University of Central Florida. Ntchito yoyambirira ndi Christine Senior. Zindikirani: Zomwe zili zingathe kusinthidwa malinga ndi kalembedwe ndi kutalika.
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Nthawi yotumiza: Sep-10-2021